Characterization of the first angiotensin-converting like enzyme in bacteria: Ancestor ACE is already active.

"this ace-like enzyme in x citri is to our knowledge the first bacterial ace-like enzyme ever characterized 2 2 1 the protein sequence of the leech ace ( tt ace genbank accession no 45272589 ) the most distant known ace characterized at the time of the present study was submitted to similarity searches using the blast program suite (tblastn; default parameters) ( http://www nih nlm ncbi gov/blast ) against all bacterial genomic sequences available at the ncbi server at the time of the study."

"This work was supported by grants from INSERM (Institut National pour la Santé et la Recherche Médicale), Region Nord Pas de Calais and CNRS (Centre National pour la Recherche Scientifique) and Wellcome Trust (U.K.) grants 070060 (K.R.A.) and 071047 (E.D.S.)."