Mouse N-acetyltransferase type 2, the homologue of human N-acetyltransferase type 1.

Publication Year: 2008

DOI:
10.1016/j.bcp.2007.12.012

PMCID:
PMC2279149

PMID:
18280460

Journal Information

Full Title: Biochem Pharmacol

Abbreviation: Biochem Pharmacol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Biochemistry

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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2/6
0.0% Transparent
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Evidence found in paper:

"a non-mutated human nat1 crystal structure has also been deposited in which the active-site cysteine residue was modified to s -(2-anilino-2-oxoethyl)-cysteine (pdb accession code: 2pqt).; however a structure of human nat2 with coenzyme a bound has also been deposited (pdb accession code: 2pfr) and the position of the coenzyme a is such that the c-terminus and inter-domain loops regions are not significantly changed."

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Evidence found in paper:

"The authors thank Lindsay Johnson and Dee Perera for help with preparation of the manuscript and James Sandy, Angela Russell and Steve Davies for helpful discussions. We are grateful to the Wellcome Trust for financial support. Kylie Walters is in receipt of a grant from the American Cancer Society."

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Open Access
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Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025