Quantification of gamma-secretase modulation differentiates inhibitor compound selectivity between two substrates Notch and amyloid precursor protein.
Journal Information
Full Title: Mol Brain
Abbreviation: Mol Brain
Country: Unknown
Publisher: Unknown
Language: N/A
Publication Details
Subject Category: Molecular Biology
Available in Europe PMC: Yes
Available in PMC: Yes
PDF Available: No
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"Competing interests The authors declare that they have no competing interests."
"AcknowledgementsWe would like to thank Dr. Dennis Selkoe for providing cDNA constructs, Dr. Michael Wolfe for providing cpd E, Dr. Peter Seubert and Dr. Dale Schenk for ELISA antibodies, Dr. Pamela Raymond for the cDNA carrying her6, Dr. Pamela Osenkowski and Wenjuan Ye for helpful discussions. This work was supported by NIH grant AG015379 (WX)."
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Last Updated: Aug 05, 2025