Improved tricyclic inhibitors of trypanothione reductase by screening and chemical synthesis.

Authors:
Richardson JL; Nett IR; Jones DC; Abdille MH; Gilbert IH and 1 more

Journal:
ChemMedChem

Publication Year: 2009

DOI:
10.1002/cmdc.200900097

PMCID:
PMC2929371

PMID:
19557801

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Journal Information

Full Title: ChemMedChem

Abbreviation: ChemMedChem

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"We thank Ahilan Saravanamuthu, for expression and purification of TryR, Dr. David Norman (Post Genomics and Molecular Interactions Centre, University of Dundee) for the NMR spectra and Dr. Stephen Patterson for useful comments. This work was supported by the Drugs for Neglected Diseases initiative (DNDi) and the Wellcome Trust (WT07938 and WT083481)."

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Last Updated: Aug 05, 2025