Novel SPG11 mutations in Asian kindreds and disruption of spatacsin function in the zebrafish.

"complete transcript sequence data have been deposited with the genbank data library under accession numbers fj217177 (full-length cdna 7140 bp) and fj217178 (alternative cdna 3747 bp)."

"Conflict of interest The authors declare that they have no conflict of interest."

"This work was supported by the Wellcome Trust (programme grant 062346/Z/00/Z, project grant 078751/Z/05/Z). The authors would like to express their gratitude to the families for participating in this study and to Shanta Patel, University Hospitals of Leicester NHS Trust, for facilitating sample collection. We also acknowledge the assistance provided in extracting, storing, and forwarding DNA samples for genetic analysis by the Human Brain Tissue Repository DNA Bank (Human Brain Bank), Department of Neuropathology, National Institute of Mental Health and Neurosciences, Bangalore."