Widespread Lewy body and tau accumulation in childhood and adult onset dystonia-parkinsonism cases with PLA2G6 mutations.

"Disclosure statement None of the authors has stated any conflict of interest. This project was approved by the Joint Local Research Ethics Committee of the National Hospital for Neurology and Neurosurgery. Brains are stored in the Queen Square Brain Bank, London (QSBB) and the Brain and Tissue Banks for Developmental Disorders, Baltimore (BTBDD) by obtaining appropriate consents."

"We are grateful to the patients and families who support the donation of tissue for research. We thank the following for essential grant support: The Bachmann Strauss Foundation (CPR, JH), The Medical Research Council (MRC; HH and JH; MRC fellowship, G108/638 and G0802760), The Michael J. Fox Foundation (HH, CPR, and JH), The Brain Research Trust (BRT, HH, JH), Ataxia UK (HH), The BMA, Vera Down Award (HH), the Sarah Matheson Trust for MSA (JLH, HH, JH, AJL, TR), and the Alzheimer's Research Trust (TR, JLH). We thank the NICHD, Brain and Tissue Bank for Developmental Disorder at the University of Maryland, Baltimore, MD. The Queen Square Brain Bank is supported by the Reta Lila Weston Institute and by grants from the Progressive Supranuclear Palsy (Europe) Association. This study was supported by the NIHR UCLH/UCL Comprehensive Biomedical Research Centre."