A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d.
Journal Information
Full Title: Mol Immunol
Abbreviation: Mol Immunol
Country: Unknown
Publisher: Unknown
Language: N/A
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Subject Category: Allergy and Immunology
Available in Europe PMC: Yes
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"the final coordinates of the sbi-iv-c3d complex have been deposited to the protein data bank (pdb accession code 2wy8 ) 2 3 preparation of uniformly 15 n-labelled sbi-iv for nmr titration experiments was carried out as described before ( )."
"This work was supported in part by Biotechnology and Biological Sciences Research Council (BBSRC) Follow-on Fund Grant BB/F528014/1 (to JMHvdE and SB) and by Wellcome Trust grant 076124 (to SB). EAC was funded by a BBSRC studentship. We would like to thank the staff at the Diamond Light Source (UK) for access to data collection facilities. Access to the DESY-EMBL beam lines was supported by the European Community-Research Infrastructure Action under the FP6 “Structuring the European Research Area Programme” Contract RII3/CT/2004/5060008. AVZ and DIS acknowledge the support from EU Design Study SAXIER, contract no. 011934. We are grateful to Professor David Isenman for reviewing the manuscript and for his helpful discussions."
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