A structural basis for Staphylococcal complement subversion: X-ray structure of the complement-binding domain of Staphylococcus aureus protein Sbi in complex with ligand C3d.

Publication Year: 2010

DOI:
10.1016/j.molimm.2010.09.017

PMCID:
PMC3025320

PMID:
21055811

Journal Information

Full Title: Mol Immunol

Abbreviation: Mol Immunol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Allergy and Immunology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"the final coordinates of the sbi-iv-c3d complex have been deposited to the protein data bank (pdb accession code 2wy8 ) 2 3 preparation of uniformly 15 n-labelled sbi-iv for nmr titration experiments was carried out as described before ( )."

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"This work was supported in part by Biotechnology and Biological Sciences Research Council (BBSRC) Follow-on Fund Grant BB/F528014/1 (to JMHvdE and SB) and by Wellcome Trust grant 076124 (to SB). EAC was funded by a BBSRC studentship. We would like to thank the staff at the Diamond Light Source (UK) for access to data collection facilities. Access to the DESY-EMBL beam lines was supported by the European Community-Research Infrastructure Action under the FP6 “Structuring the European Research Area Programme” Contract RII3/CT/2004/5060008. AVZ and DIS acknowledge the support from EU Design Study SAXIER, contract no. 011934. We are grateful to Professor David Isenman for reviewing the manuscript and for his helpful discussions."

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Last Updated: Aug 05, 2025