Lysosomal dysfunction increases exosome-mediated alpha-synuclein release and transmission.

Authors:
Alvarez-Erviti L; Seow Y; Schapira AH; Gardiner C; Sargent IL and 2 more

Journal:
Neurobiol Dis

Publication Year: 2011

DOI:
10.1016/j.nbd.2011.01.029

PMCID:
PMC3107939

PMID:
21303699

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Journal Information

Full Title: Neurobiol Dis

Abbreviation: Neurobiol Dis

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"The authors declare no conflicts of interest."

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"This work was supported by the Brain Research Trust (LA), Parkinson's Disease UK, the Wellcome/MRC Parkinson's Disease Consortium grant to UCL/IoN, the University of Sheffield and the University of Dundee. The Nanoparticle Tracking Analysis work was supported by the Wellcome Trust (Grant Ref GR087730) and the Oxford Partnership Comprehensive Biomedical Research Centre with funding from the Department of Health's NIHR Biomedical Research Centres funding scheme. The assistance of Professor John Morris with the electron microscopy and Dr KY Chau for the confocal analyses was greatly appreciated."

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