Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk.

"Potential conflict of interest: Nothing to report."

"Luigi Naldini was supported by grants from the 7th European Union Framework Programme (agreement 222878, PERSIST) and Telethon (TIGET grant). Maria Grazia Roncarolo was supported by Telethon (TIGET grant). Thierry VandenDriessche was supported by PERSIST, the Bayer-Schering Hemophilia Special Project Award, the Fund for Scientific Research (FWO & FWO-Wetenschappelijke Onderzoeksgemeenschap), “Geconcentreerde Onderzoek Acties” GOA-EPIGEN (Free University of Brussels), European Hematology Association (EHA) and Association Française contre les Myopathies (AFM) and Stichting tegen Kanker (STK). Marinee Chuah was supported by PERSIST, the Fund for Scientific Research (FWO & FWO-Wetenschappelijke Onderzoeksgemeenschap), “Geconcentreerde Onderzoek Acties” GOA-EPIGEN (Free University of Brussels) and EHA; Janka Mátrai was supported by PERSIST and EHA (No.: 2010/21)."