Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors.

Publication Year: 2011

DOI:
10.1002/cmdc.201100144

PMCID:
PMC3170876

PMID:
21608132

Journal Information

Full Title: ChemMedChem

Abbreviation: ChemMedChem

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"This work was supported by Sterix Ltd,a member of the Ipsen Group, and by the Wellcome Trust Programme Grant 082837 to B.V.L.P. We thank Alison C. Smith for technical assistance, Nicole Muller and Isabelle Viossat for CYP inhibition and metabolic stability studies. We also thank the EPSRC national mass spectrometry service centre at the University of Wales Swansea for taking some high resolution accurate mass measurements."

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Last Updated: Aug 05, 2025