Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept.

"Dr Kaddurah-Daouk is an equity holder in Metabolon, a biotechnology company in the metabolomics domain, and also an inventor on patents in the metabolomics field. She has received funding or consultancy fees for BMS, Pfizer, AstraZeneca and Lundbeck. Dr Ranga Krishnan has served as a consultant for Amgen, Bristol-Myer Squibb, CeNeRx, Corcept, GlaxoSmithKline, Johnson & Johnson, Lundbeck, Merck, Organon, Pfizer, Sepracor and Wyeth. Additionally, he is an inventor on patents in the metabolomics field. Dr Wayne Matson is an inventor on patents in the metabolomics field. A John Rush has received consulting fees from Advanced Neuromodulation Systems, Best Practice Project Management, Otsuka, University of Michigan and Brain Resource; consultant/speaker fees from Forest Pharmaceuticals; consultant fees and is a stockholder of Pfizer; other royalties from Guilford Publications, Healthcare Technology Systems and the University of Texas Southwestern Medical Center and research support from the National Institute of Mental Health."

"We would like to thank Dorothy Peters for her assistance in preparation of this manuscript and also acknowledge the editorial support of Jon Kilner (Pittsburgh, PA, USA). This work was done with funding from Pfizer corporation and from NIGMS grant GM078233, ‘The Metabolomics Research Network for Drug Response Phenotype' (RKD, WM, SB, EC)."