Serious infection and mortality in patients with Crohn's disease: more than 5 years of follow-up in the TREAT™ registry.

"Guarantor of the article: Gary R. Lichtenstein, MD.: Specific author contributions: Gary R. Lichtenstein, Brian G. Feagan, Russell D. Cohen, Bruce A. Salzberg, Robert H. Diamond, and William J. Sandborn were involved in the registry design and conduct; Robert H. Diamond, Samiyeh Price, Wayne Langholff, and Anil Londhe were involved in data collection and analysis; and all authors provided critical content review and final approval of this manuscript.: Financial support: Funding for the TREAT registry is provided by Janssen Biotech Inc., a Johnson and Johnson (J&J) pharmaceutical company.: Potential competing interests: Dr. Lichtenstein has received research grants and/or has served as a consultant for Abbott, Alaven, Bristol-Myers Squibb, Elan, Ferring, Janssen, Meda Pharmaceuticals, Millenium Pharmaceuticals, Pfizer Pharmaceuticals, Proctor and Gamble, Prometheus Laboratories, Salix Pharmaceuticals, Santarus, Merck/Schering-Plough, Shire Pharmaceuticals, UCB, Warner Chilcotte, and Wyeth. Dr. Feagan has received research grants and/or has served as a consultant for Abbott, Actogenix, Alba Therapeutics, Albireo Pharma, Astra Zeneca, Athersys, Axcan, Berlex, Boehringer Engelheim, Bristol-Myers Squibb, Celgene, Cerimon Pharma, CombinatoRx, Elan/Biogen, Funxional Therapeutics, GeneLogic, Genentech, Given Imaging, Gilead, Glaxo Smithkline, ISIS, Janssen, Merck/Schering-Plough, Millennium, Napo Pharma, Nektar, Novartis, Novonordisk, Ore Pharm. (previously GeneLogic), Osiris, Otsuka, Pfizer, Proctor and Gamble, Prometheus Therapeutics and Diagnostics, Protein Design Labs, Salix Pharma, Santarus, Schering Canada, Serono, Shire, Synta, Teva Pharma, Tillotts Pharma AG, Tioga Pharma, UCB Pharma, Unity Pharma, Wyeth, and Zealand Pharma. Dr Cohen has received research grants and/or has served as a consultant for Janssen. Dr Salzberg has received consulting and/or speaker fees for Abbott Laboratories, Janssen, and Shire. Dr Sandborn has received consulting fees and research support from Abbott Laboratories, Janssen, and UCB Pharma, as well as consulting fees from Merck/Schering-Plough. R.H. Diamond and S. Price are employed by Janssen, a J&J company, and own stock in J&J. W. Langholff and A. Londhe are employees of J&J Pharmaceutical Research Division and own stock in J&J."

"Financial support: Funding for the TREAT registry is provided by Janssen Biotech Inc., a Johnson and Johnson (J&J) pharmaceutical company."