Depletion of PAK1 enhances ubiquitin-mediated survivin degradation in pancreatic β-cells.

Authors:
Chen YC; Fueger PT; Wang Z.

Journal:
Islets

Publication Year: 2013

DOI:
10.4161/isl.24029

PMCID:
PMC3662379

PMID:
23514967

Journal Information

Full Title: Islets

Abbreviation: Islets

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Gastroenterology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
2/6
0.0% Transparent
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Evidence found in paper:

"Disclosure of Potential Conflicts of Interest No potential conflicts of interest were disclosed."

Evidence found in paper:

"Y.C. contributed data for Figure 1 and Figure 7. P.F. helped interpret the data and edited the manuscript. Z.W. designed the project, contributed data for Figure 1–7, and wrote the manuscript. This study was supported by CTSI-KL2 RR025760 (to Z. W.). We are grateful to Dr Lawrence Quilliam (Indiana University School of Medicine) and Dr John Hutton (University of Colorado Health Sciences Center) for their gifts of the pCMV-myc-PAK1 plasmid and MIN6 cells, respectively. We thank Dr Stephanie Yoder for providing the mice, Dr Michael Kalwat for technique assistance, as well as Natalie Stull for assistance with islet isolation."

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Open Access
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Last Updated: Aug 05, 2025