Vascular and Alzheimer's disease markers independently predict brain atrophy rate in Alzheimer's Disease Neuroimaging Initiative controls.

"Disclosure statement Josephine Barnes: Dr Barnes has received honoraria for reviewing grants for the Fundação para a Ciência e a Tecnologia-Portugal and was supported by an Alzheimer's Research UK fellowship. Gerard R Ridgway: Dr Ridgway serves as an editorial board member for NeuroImage and has received honoraria for teaching on SPM courses. Jonathan M Schott: Dr Schott is a UK HEFCE Senior Lecturer and receives grant support from Alzheimer's Research UK Martin N Rossor: Professor Martin Rossor sits on the Data Monitoring Committee for Servier DMC Phase 2B AD Study S38093, and also sits on the Bapineuzumab Independent Safety Monitoring Committee for Janssen Al/Pfizer. Charlie DeCarli: Dr DeCarli is editor-in-Chief of ADAD. He has received honoraria for speaking at various academic centers and teaching at the AAN and has consulted with Avid and Takeda over the last year. Nick C Fox: Dr Fox has served on the scientific advisory boards of Alzheimer's Research Forum, Alzheimer's Society and Alzheimer's Research Trust and editorial boards of Alzheimer's Disease and Associated Disorders, Neurodegenerative Diseases, and Alzheimer's Research and Therapy. He holds a patent for QA Box that may accrue revenue. In the last 5 years his research group has received payment for consultancy or for conducting studies from Abbott Laboratories, AstraZeneca, AVID, Bristol-Myers Squibb, Elan Pharmaceuticals, Eisai, Eli Lilly, GE Healthcare, IXICO, Janssen (JAI), Lundbeck, Neurochem Inc, Pfizer Inc, Sanofi-Aventis, Teva and Wyeth Pharmaceuticals. He receives research support from MRC [G0801306 (PI), G0601846 (PI)] NIH [U01 AG024904 (Co-investigator(sub contract)], Alzheimer Research Trust [ART/RF/2007/1 (PI)] and NIHR (Senior Investigator). None of the other authors have any conflicts of interest to declare."

"This work was supported by the Medical Research Council [grant numbers GO 601846, MR/J014257/1]. JMS is a HEFCE/NHS Clinical Senior Lecturer and is supported by the Alzheimer Research UK. The research was funded/supported by the National Institute for Health Research (NIHR) Biomedical Research Unit in Dementia based at University College London Hospitals (UCLH), University College London (UCL). The views expressed are those of the author(s) and not necessarily those of the NHS, the NIHR or the Department of Health. The Dementia Research Centre is an Alzheimer's Research UK Co-ordinating Centre. This work was made possible with an Alzheimer's Research UK Equipment Grant. The Wellcome Trust Centre for Neuroimaging is supported by core funding from the Wellcome Trust [grant number 091593/Z/10/Z]. Data collection and sharing for this project was funded by the Alzheimer's Disease Neuroimaging Initiative (ADNI) (National Institutes of Health Grant U01 AG024904). ADNI is funded by the National Institute on Aging, the National Institute of Biomedical Imaging and Bioengineering, and through generous contributions from the following: Abbott; Alzheimer's Association; Alzheimer's Drug Discovery Foundation; Amorfix Life Sciences Ltd; AstraZeneca; Bayer HealthCare; BioClinica, Inc; Biogen Idec Inc; Bristol-Myers Squibb Company; Eisai Inc; Elan Pharmaceuticals Inc; Eli Lilly and Company; F. Hoffmann-La Roche Ltd and its affiliated company Genentech, Inc; GE Healthcare; Innogenetics, N.V.; Janssen Alzheimer Immunotherapy Research & Development, LLC.; Johnson & Johnson Pharmaceutical Research & Development LLC.; Medpace, Inc; Merck & Co, Inc; Meso Scale Diagnostics, LLC.; Novartis Pharmaceuticals Corporation; Pfizer Inc; Servier; Synarc Inc; and Takeda Pharmaceutical Company. The Canadian Institutes of Health Research is providing funds to support ADNI clinical sites in Canada. Private sector contributions are facilitated by the Foundation for the National Institutes of Health (www.fnih.org). The grantee organization is the Northern California Institute for Research and Education, and the study is coordinated by the Alzheimer's Disease Cooperative Study at the University of California, San Diego. ADNI data are disseminated by the Laboratory for Neuro Imaging at the University of California, Los Angeles. This research was also supported by NIH grants P30 AG010129, K01 AG030514, and the Dana Foundation."