DUSP1 Gene Polymorphisms Are Associated with Obesity-Related Metabolic Complications among Severely Obese Patients and Impact on Gene Methylation and Expression.

"Conflict of Interests The authors declare no conflict of interests. "

"The authors express their gratitude to surgeons Simon Biron, Odette Lescelleur, Laurent Biertho, and Simon Marceau of the Laval Hospital bariatric surgery team, who have sampled adipose tissues for this project. Many thanks are also expressed to Caroline Nadeau for her help in management of the adipose tissue banking. The authors would like to acknowledge the contribution of Alain Houde and Valérie Turcot for sample management and technical assistance. F. Guénard is a recipient of a Research Fellowship Award from the Heart and Stroke Foundation of Canada. L. Bouchard is a junior research scholar from the Fonds de la Recherche en Santé du Québec (FRSQ) and member of the FRSQ-funded Centre de Recherche Clinique Étienne-Le Bel (affiliated to Centre Hospitalier de l'Université de Sherbrooke). A. Tchernof is the recipient of a Research Chair in Bariatric and Metabolic Surgery. M.  C. Vohl is the recipient of the Canada Research Chair in Genomics Applied to Nutrition and Health. This study was supported by a Grant from the Canadian Institutes of Health Research (CIHR MOP-209380). The severely obese cohort was supported, over the years, by the Laval University Merck Frosst/CIHR Research Chair in Obesity."