Morphometry of the hippocampal microvasculature in post-stroke and age-related dementias.

"Disclosure statements for authors The co-authors have no disclosures with regard to this report. The study was not industry-sponsored. There are no conflicts of interest. The individual contributor statements are as follows:Matthew C.J. Burke performed the experimental work and the analysis and wrote several drafts.Lucy Nelson contributed to collection of the data and particularly performed stereological analysis of the microvasculature in other brain areas.Janet Y. Slade performed the initial immunocytochemical analysis and advised on the analysis.Arthur E. Oakley advised on and interpreted the stereological analysis and corrected drafts of the manuscript.Ahmad A. Khundakar advised on and interpretation of the stereological analysis.Raj N. Kalaria conceived the study, performed some of the neuropathological analysis, corrected several drafts and obtained the funding. Conflicts of interest None declared."

"We are very grateful to the patients, families and clinical staff for their cooperation and help with the execution of this pathological follow up study. We are indebted to Dr Yumi Yamamoto (Yamaguchi, Japan) for fruitful discussions and devising vessel diameter software and to Dr Tuomo M. Polvikoski for the assistance on neuropathological analysis. We are grateful to Ms Elizabeth Gemmell and Dr Rufus Akinyemi for their work on Thal staging. Our work is supported by grants from the Newcastle Centre for Brain Ageing and Vitality (BBSRC, EPSRC, ESRC and MRC, LLHW), UK Medical Research Council (MRC, G0500247) and the Alzheimer's Research UK (UK). Tissue for this study was collected by the Newcastle Brain Tissue Resource, which is funded in part by a grant from the UK MRC (G0400074), by the Newcastle NIHR Biomedical Research Centre in Ageing and Age Related Diseases award to the Newcastle upon Tyne Hospitals NHS Foundation Trust, and by a grant from the Alzheimer's Society and Alzheimer's Research UK (ARUK) as part of the Brains for Dementia Research Project. This work was only possible with a ARUK studentship award to M.C.J.B."