CSNK1E/CTNNB1 are synthetic lethal to TP53 in colorectal cancer and are markers for prognosis.

"the dataset used is shown in supplementary dataset s1.; supplementary figures supplementary tables supplementary dataset s1 supplementary text s1 supplementary text s2 supplementary materials and methods acknowledgment this paper is dedicated to the memory of the late dr."

"The authors declare no conflict of interest."

"This paper is dedicated to the memory of the late Dr. Konan Peck, who kindly let K.-L.T. conduct the biological experiments in his lab for over one year, and whose helpful discussions were greatly appreciated. We thank Tzu-Cheng Su for examining IHC images; Cheng-Wen Wu, Zee-Fen Chang and Bert Vogelstein for CRC cells; Mei-Jung Wang for her technical assistance; Hsuan-Yu Chen and Yi-Chung Chang for helpful discussions. This work was supported by National Science Council of R.O.C. [NSC100-2118-M-001-003-MY2 and NSC102-2314-B-001-005 to G.S.S., NSC102-2320-B-039-039 to J.-G.C.], Taiwan Ministry of Health and Welfare Cancer Research Center for Excellence [MOHW103-TD-B-111-03 to J.-G.C.] and China Medical University Hospital [DMR-103-017 to J.-G.C.]."