The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge.
Journal Information
Full Title: Immunobiology
Abbreviation: Immunobiology
Country: Unknown
Publisher: Unknown
Language: N/A
Publication Details
Subject Category: Allergy and Immunology
Available in Europe PMC: Yes
Available in PMC: Yes
PDF Available: No
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"Conflict of interest There are no conflicts of interest."
"We thank Professor David Hume and Dr Kristin Sauter (Roslin Institute, University of Edinburgh) for the MacGreen CSF-1R GFP reporter mice hearts. Also thanks to the Rick Maizels’ lab (Institute of Immunology and Infection Research, University of Edinburgh) for carrying out the infections and providing hearts from the H. polygyrus infected mice. This work was supported by The Wellcome Trust (WT091720MA)."
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Last Updated: Aug 05, 2025