Sequence variation in mature microRNA-608 and benefit from neo-adjuvant treatment in locally advanced rectal cancer patients.

"Conflict of Interest Statement: D.C. received research funding from: Roche, Amgen, Celgene, Sanofi, Merck Serono, Novartis, AstraZeneca, Bayer, Merrimack and MedImmune. C.P. has had advisory roles with Sanofi. J.T. has had advisory roles with Amgen, Roche, Sanofi-Aventis, and Merck. A.C. has had advisory roles with Merck-Serono and Roche. He has received research funding from Roche and honoraria from Roche and Merck-Serono. I.C. has had advisory roles with Merck Serono, Roche, Sanofi Oncology, Bristol Myers Squibb, Eli-Lilly, Novartis, Gilead Science. He has received research funding from Merck-Serono, Novartis, Roche and Sanofi Oncology, and honoraria from Roche, Sanofi-Oncology, Eli-Lilly, Taiho. All other authors declare no conflict of interest."

"Funding The work was supported by Cancer Research UK (CEA A18052), European Union FP7 (CIG 334261) and the National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research (grant A62) to N.V."

"The study was approved by local ethics committees and institutional review boards and written informed consent was obtained from each patient before study entry including consent for future research (ISRCTN registration: 99828560)."