Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status.

"Disclosures None."

"Sources of Funding G. Rena acknowledges funding from MRC (MR/K012924/1) and the Diabetes UK RW and JM Collins studentship, supporting C. Forteath (12/0004625). S.C. Fagerholm acknowledges funding from the Academy of Finland and Biocentrum Helsinki. M. Foretz acknowledges funding from the Région Ile de France-CORDDIM and by the Société Francophone du Diabète. C.C. Lang acknowledges support from the British Heart Foundation (grant number PG/06/143/21897 and PG/14/4/30539). A.K.F. Wong acknowledges support from the British Heart Foundation (grant number PG/06/143/21897). M. Mohan. acknowledges fellowship support from the British Heart Foundation (grant number PG/14/4/30539). V.L. Morrison was supported by the Ella and Georg Ehrnrooth foundation and D.J.K. Balfour acknowledges funding from Alzheimer’s Research UK, grant number ART-EXT-2010–2. C. Beall is an RD Lawrence Fellow (Diabetes UK grant number: 13/00004647)."

"Clinical Trial Registration: Name of the trial registry: TAYSIDE trial (Metformin in Insulin Resistant Left Ventricular [LV] Dysfunction). URL: https://www.clinicaltrials.gov. Unique identifier: NCT00473876."