Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein.

Authors:
Joiner S; Asante EA; Linehan JM; Brock L; Brandner S and 5 more

Journal:
J Neurol Sci

Publication Year: 2017

DOI:
10.1016/j.jns.2017.12.038

PMCID:
PMC5946165

PMID:
29406965

View on PubMed View on PMC View Publisher
Journal Information

Full Title: J Neurol Sci

Abbreviation: J Neurol Sci

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"Competing interests J.C. is a Director and J.C. and J.D.F.W. are shareholders of D-Gen Limited, an academic spin-out company working in the field of prion disease diagnosis, decontamination, and therapeutics. D-Gen owns the ICSM35 antibody used in this study. The other authors declare no potential conflicts of interest."

Evidence found in paper:

"Funding This work was funded by the Medical Research Council (MC U123160655). Some of the work was undertaken at University College London Hospital NHS Foundation Trust which received a proportion of funding from the Department of Health's (BRC 405/HI/JC/104360) NIHR Biomedical Research Centres funding scheme."

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Last Updated: Aug 05, 2025