Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.

"patient i's detailed description is in the supplementary data 3 4 we followed up our findings checking csf1r expression in load and control brain samples."

"Disclosure statement All the authors declare no competing financial or personal interests that can influence the presented work. However, MAN's participation is supported by a consulting contract between Data Tecnica International and the National Institute on Aging NIH, Bethesda, MD, USA, as a possible conflict of interest, and he also consults Illumina Inc, the Michael J. Fox Foundation, and the University of California Healthcare among others."

"This study was supported by the Alzheimer's Research UK, the Medical Research Council (MRC), the Wellcome Trust/MRC Joint Call in Neurodegeneration Award (WT089698) to the UK Parkinson's Disease Consortium (whose members are from the University College London Institute of Neurology, the University of Sheffield, and the MRC Protein Phosphorylation Unit at the University of Dundee), grants (P50 AG016574, U01 AG006786, and R01 AG18023), the National Institute for Health Research Biomedical Research Unit in Dementia at University College London Hospitals, University College London; the Big Lottery (to KM); JB and RG's work is funded by fellowships from the Alzheimer's Society; Humboldt Fellowship (to CS) and the Intramural Research Programs of the National Institute on Aging and the National Institute of Neurological Disease and Stroke, National Institutes of Health (Department of Health and Human Services Project number, ZO1 AG000950-10). MAN's participation is supported by a consulting contract between Data Tecnica International and the National Institute on Aging NIH, Bethesda, MD, USA. The MRC London Neurodegenerative Diseases Brain Bank and the Manchester Brain Bank from Brains for Dementia Research are jointly funded from ARUK and AS. The Alzheimer's Research UK (ARUK) Consortium funded PP, DC, JJ, BMcG, ST, Queen's University Belfast, UK; RH, Royal Derby Hospital, UK; HK, University of Bonn, Germany; PGK, University of Bristol, UK; NMH, University of Leeds, UK; ERLCV, University of Newcastle, UK; DMM, SP-B, University of Manchester, UK; KB, JL, KM, University of Nottingham, UK; ADS, GW, DW, University of Oxford (OPTIMA), UK; CH, University of Southampton, UK. Tissue samples were supplied by The London Neurodegenerative Diseases Brain Bank, which receives funding from the MRC and as part of the Brains for Dementia Research programme, jointly funded by Alzheimer's Research UK and Alzheimer's Society."