Bone matrix development in steroid-induced osteoporosis is associated with a consistently reduced fibrillar stiffness linked to altered bone mineral quality.

"appendix a supplementary data the following are the supplementary data to this article: supplementary data 1 acknowledgements this work was supported by diamond light source (harwell uk) and queen mary university of london (grant no seml1b4r); and the medical research council uk (grant no g0600702)."

"This work was supported by Diamond Light Source (Harwell, UK) and Queen Mary University of London (grant no. SEML1B4R); and the Medical Research Council UK (grant no. G0600702). L.X. is supported by the China Scholarship Council (CSC). N.M.P. is supported by the European Commission under the Graphene Flagship Core2 No. 785219 (WP14 “Polymer Composites”) and FET Proactive “Neurofibres” grant No. 732344. EB acknowledges funding from the JSPS KAKENHI Grant Number JP18K18065. We thank Diamond Light Source (Harwell, UK) for the generous award of synchrotron beamtime to carry out the in situ SAXD experiments (SM9893, SM11806, and SM12483), as well as Dr. Andrew Smith and Dr. Olga Shebanova for excellent technical support during the beamtimes."