Integrated analysis of 8-week glecaprevir/pibrentasvir in Japanese and overseas patients without cirrhosis and with hepatitis C virus genotype 1 or 2 infection.

"Conflict of interest Atsushi Naganuma and Kazuo Notsumata have nothing to disclose. Kazuaki Chayama received research funding from AbbVie, Bristol-Myers Squibb, Dainippon Sumitomo Pharma, Toray Industries, Inc. and received payment for lectures from AbbVie, Bristol-Myers Squibb, Gilead, and MSD. Edward Gane is an advisor for AbbVie, Alnylam, Arbutus, Assembly, Arrowhead, Enanta, Gilead Sciences, Janssen, Merck, Novartis, Novira, Roche, and VIR, and participated in speakers’ bureaus for AbbVie, Gilead Sciences. Graham Foster received grants from AbbVie, Gilead, and Merck, and consulted and participated in speakers’ bureaus for AbbVie, MSD, and Gilead. David Wyles received research funding (paid to his institution) from AbbVie, Gilead and Merck, and served as consultant to AbbVie, Gilead and Merck. Paul Kwo participated on advisory committees or review panels for AbbVie, Abbott, Merck, Gilead, Bristol-Meyers Squibb, Janssen, Alnylam, and Inovio, and received grant/research support from AbbVie, Merck, Bristol-Meyers Squibb, Janssen, Gilead, Merck, and Conatus. Eric Crown, Abhi Bhagat, Margaret Burroughs, Federico Mensa, Tetsuya Otani, and Lois Larsen are employees and may hold stock or options. Hiromitsu Kumada received payment for lectures from AbbVie GK, MSD, Dainippon Sumitomo Pharma, Bristol-Myers Squibb, and Gilead."

"Funding AbbVie sponsored the studies, contributed to their design, collection, analyses, integrated analysis, and interpretation of the data, and participated in the writing, review, and approval of the manuscript. All authors had access to relevant data. AbbVie is committed to responsible data sharing regarding the clinical trials we sponsor. This includes access to anonymized, individual and trial-level data (analysis data sets), as well as other information (e.g., protocols and Clinical Study Reports), as long as the trials are not part of an ongoing or planned regulatory submission. This includes requests for clinical trial data for unlicensed products and indications. This clinical trial data can be requested by any qualified researchers who engage in rigorous, independent scientific research, and will be provided following review and approval of a research proposal and Statistical Analysis Plan (SAP) and execution of a Data Sharing Agreement (DSA). Data requests can be submitted at any time and the data will be accessible for 12 months, with possible extensions considered. For more information on the process, or to submit a request, visit the following link: https://www.abbvie.com/our-science/clinical-trials/clinical-trials-data-and-information-sharing/data-and-information-sharing-with-qualified-researchers.html."

"ClinicalTrials.gov identifiers The trials discussed in this paper were registered with ClinicalTrials.gov as follows: NCT02707952 (CERTAIN-1), NCT02723084 (CERTAIN-2), NCT02243280 (SURVEYOR-I), NCT02243293 (SURVEYOR-II), NCT02604017 (ENDURANCE-1), NCT02738138 (EXPEDITION-2)."