Heterozygosity mapping for human dominant trait variants.

"all vcf files (other than those from the alspac collection) used in our manuscript have been deposited with the european genome-phenome archive (ega) wellcome trust genome campus hinxton cambridge cb10 1 sd uk with study accession number egas00001002837."

"CONFLICT OF INTERESTS The authors declare that there are no conflicts of interests."

"We thank Prof. J. Felsenstein at the University of Washington, Seattle, for helpful discussions on this project. This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI, grant Number JP16K19404 (A. I.), by JSPS KAKENHI, grant number JP18K15863 (A. I.), by NSFC China project, grants 3147 0070 (J. O.) and 3150 1002 (Y. L.), by the Taiwan Minister of Science and Technology: MOST 106‐2314‐B‐001‐004‐MY2 (C. S. J. F.), and by the U.S. National Institutes of Health, grants DC011651, DC003594, AG058131, HG008972, and HG006493 (S. M. L.). The UK Medical Research Council, Wellcome (grant ref: 102215/2/13/2), and the University of Bristol provide core support for ALSPAC. A comprehensive list of grants funding is available on the ALSPAC website (http://www.bristol.ac.uk/alspac/external/documents/grant‐acknowledgements.pdf); this research was specifically funded by WT091310. This publication is the work of the authors and C. S. J. Fann will serve as guarantor for the contents of this paper."