Ageing-associated changes in the expression of lncRNAs in human tissues reflect a transcriptional modulation in ageing pathways.

Authors:
Marttila S; Chatsirisupachai K; Palmer D; de Magalhães JP.

Journal:
Mech Ageing Dev

Publication Year: 2019

DOI:
10.1016/j.mad.2019.111177

PMCID:
PMC6961210

PMID:
31706952

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Journal Information

Full Title: Mech Ageing Dev

Abbreviation: Mech Ageing Dev

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Geriatrics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"in the present study we characterised the ageing-associated changes in lncrna expression in 29 healthy human tissues between the ages20 and 79 years using the data available in 2 2 1 the data used for the analyses described in this manuscript were obtained from gtex project dbgap accession number phs000424 v7."

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Evidence found in paper:

"The Genotype-Tissue Expression (GTEx) Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health, and by NCI, NHGRI, NHLBI, NIDA, NIMH, and NINDS. SM is supported by Osk. Huttunen Foundation and Orion Research Foundation. DP is supported by a Leverhulme Trust grant (RPG-2016-015) to JPM. GeneFriends is supported by a Wellcome Trust grant (208375/Z/17/Z) to JPM."

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Last Updated: Aug 05, 2025