Selection of In Vivo Predictive Dissolution Media Using Drug Substance and Physiological Properties.
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Full Title: AAPS J
Abbreviation: AAPS J
Country: Unknown
Publisher: Unknown
Language: N/A
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"We are grateful for the discussions on pKa and buffer capacity with Dr. Alex Avdeef. We would also like to acknowledge Dr. Brian Krieg for discussions regarding calculations of predicted dissolution rate of acidic and basic drugs in bicarbonate and “equivalent” buffers and access to his MATLAB script. We thank Simulations Plus (Lancaster, California) for providing the Drug Delivery Group at the Department of Pharmacy, Uppsala University, with a reference site license for the software ADMET Predictor. The authors declare no conflicts of interest."
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Last Updated: Aug 05, 2025