Orthotopic Bone Regeneration within 3D Printed Bioceramic Scaffolds with Region-Dependent Porosity Gradients in an Equine Model.

"Conflict of Interest: The authors declare no conflict of interest."

"P.D. and R.V.B. contributed equally to this work. P.D. acknowledges the funding from the Royal Thai Government scholarship (Thailand). P.D., S.C., M.vR., J.dG., R.vW., R.L., and J.M. acknowledge the Dutch Arthritis Society (CO-14-1-001, LLP-12 and LLP-22), and the European Research Council (grant agreement #647426, 3DJOINT). The primary antibodies against collagen type II (II-II6B3) developed by T. F. Linsenmayer and E.S. Engvall, respectively, were obtained from the DSHB developed under the auspices of the NICHD and maintained by the University of lowa, Department of Biology, lowa City, IA, USA. After initial online publication, J.M. was made a corresponding author on May 20, 2020."