Selective monitoring of insulin secretion after CRISPR interference in intact pancreatic islets despite submaximal infection.

Authors:
Shariati K; Pappalardo Z; Chopra DG; Yiv N; Sheen R and 1 more

Journal:
Islets

Publication Year: 2020

DOI:
10.1080/19382014.2020.1752072

PMCID:
PMC7527018

PMID:
32579048

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Journal Information

Full Title: Islets

Abbreviation: Islets

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Gastroenterology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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"This work was supported by NIH R01 DK107650, R01 DK118337, and K08 DK087945 and P30 DK063720 (a Pilot and Feasibility Grant to GK and core laboratories). GMK was supported by a Career Development Award from JDRF (5-CDA-2014-199-A-N). We would like to thank Michael S. German and Gerold M. Grodsky for helpful discussions; Vi Dang, Vinh Nguyen and Greg Szot from the UCSF Mouse Islet Production Core for providing pancreatic islets. The UCSF Islet Isolation Facility is supported by Diabetes Research Center (DRC) grant NIH P30 DK063720."

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Last Updated: Aug 05, 2025