Novel F8 and F9 gene variants from the PedNet hemophilia registry classified according to ACMG/AMP guidelines.

"CONFLICT OF INTERESTS The authors declare that there are no conflict of interests."

"This study is supported by the PedNet Haemophilia Research Foundation and by grants from The Swedish Research Council (2015‐02957). Unrestricted sponsorship for the PedNet Haemophilia Foundation is currently received from Bayer AG, Novo Nordisk Healthcare AG, Pfizer SRL, CSL Behring GmbH, Swedish Orphan Biovitrium AB, Takeda, Hoffmann La‐Roche."

"Data were retrieved from the “PedNet Registry,” a database which is owned and administered by the “PedNet Haemophilia Research Foundation,” consisting of 31 international hemophilia treatment centers in 18 countries and registered at ClinicalTrials.gov at NCT02979119. A complete list of PedNet members is added in the Appendix. Approval for data collection was obtained from each center's ethical review board, and written informed consent was obtained from the parents or guardians of all participants, in accordance with the Declaration of Helsinki."