Microanatomy of the Human Atherosclerotic Plaque by Single-Cell Transcriptomics.

Authors:
Depuydt MAC; Prange KHM; Slenders L; Örd T; Elbersen D and 18 more

Journal:
Circ Res

Publication Year: 2020

DOI:
10.1161/CIRCRESAHA.120.316770

PMCID:
PMC7641189

PMID:
32981416

Journal Information

Full Title: Circ Res

Abbreviation: Circ Res

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Vascular Diseases

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
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Evidence found in paper:

"r scripts are available on github [ https://github com/atheroexpress/microanatomyhumanplaque_scrnaseq ]."

Evidence found in paper:

"Disclosures None."

Evidence found in paper:

"Sources of Funding This work was supported by The Dutch Heart Foundation (CVON2017-20: Generating the best evidence-based pharmaceutical targets and drugs for atherosclerosis [GENIUS II] to J. Kuiper, M.P.J de Winther, G. Pasterkamp, S.W. van der Laan, M.A.C. Depuydt, I. Bot, B. Slütter); Spark-Holding BV (grant number 2015B002 to M.P.J de Winther); NWO-ZonMW (Dutch Research Council - The Netherlands Organization for Health Research and Development; Programma Translationeel Onderzoek [PTO] program Inhibition of mast cell activation in atherosclerotic lesions using an anti-IgE antibody approach (grant number 95105013 to M.A.C. Depuydt, I. Bot, and J. Kuiper); the European Union (Innovative Training Networks [ITN]-grant EPIMAC to M.P.J de Winther); Fondation Leducq (Transatlantic Network Grants to M.P.J de Winther, C.K. Glass, S. Yla-Herttuala, and G. Pasterkamp); EU 755320 Taxinomisis grant (G.J. de Borst, A. Boltjes, G. Pasterkamp). We acknowledge the European Research Area Network on Cardiovascular Diseases (ERA-CVD, grant number 01KL1802 to S.W. van der Laan, G. Pasterkamp); the ERA-Endless consortium (Dutch Heart Foundation, grant number 2017/T099 to H.M. den Ruijter and G. Pasterkamp), European Research Council (ERC) consolidator grant (grant number 866478 UCARE to H.M. den Ruijter). M.U. Kaikkonen was supported by the ERC under the European Union’s Horizon 2020 research and innovation programme (grant number 802825 to M.U. Kaikkonen), the Academy of Finland (Decisions 287478 and 319324), the Finnish Foundation for Cardiovascular Research, and the Sigrid Jusélius Foundation. T. Örd and M.U. Kaikkonen were supported by the Health from Science Academy Programme of Academy of Finland (TERVA) Programme of the Academy of Finland (Decision 314554). T. Lönnberg was supported by the Academy of Finland (Decisions 311081 and 314557)."

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Tool: rtransparent

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Last Updated: Aug 05, 2025