The histone and non-histone methyllysine reader activities of the UHRF1 tandem Tudor domain are dispensable for the propagation of aberrant DNA methylation patterning in cancer cells.

"raw idat files (available at ncbi geo: gse147518 gse148086) were converted to methylation beta values in r by the command opensesame [ ]. raw data for both reader and histone peptide microarrays are available in additional file 2 availability of data and materials methylation epic array: gene expression omnibus gse147518"

"Competing interests B.D.S and M.T.B. are co-founders of Epicypher, Inc. The other authors declare that they have no competing interests."

"Funding Research reported in this publication was supported by the National Institutes of Health under award numbers F99CA245821 (R.M.V.), R35GM124736 (S.B.R.), R01GM126421 (M.T.B.), and R21CA216673 (S.V.F. and B.D.S.). The Protein Array and Analysis Core is supported by a grant from Cancer Prevention and Research Institute of Texas, CPRIT RP 180804 (M.T.B.). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health."