The comprehensive study on the therapeutic effects of baicalein for the treatment of COVID-19 in vivo and in vitro.

"Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"This work was supported by grants from the Chinese Academy of Medical Sciences Emergency Project of COVID-19 (2020HY320001), CAMS Innovation Fund for Medical Sciences (2017-I2M-1-010, and 2016-I2M-3-007, China), and Technology Major Projects for “Major New Drugs Innovation and Development” (2018ZX09711001-012). Junke Song: Methodology, Data curation, Writing - original draft, Writing - review & editing. Li Zhang: Methodology, Validation, Investigation. Yanfeng Xu: Methodology. Dezhi Yang: Methodology, Validation, Investigation. Li Zhang: Methodology. Shiying Yang: Methodology. Wen Zhang: Methodology, Data curation. Jinhua Wang: Methodology. Shuo Tian: Methodology. Shengqian Yang: Methodology. Tianyi Yuan: Methodology. Ailin Liu: Methodology. Qi Lu: Methodology. Fengdi Li: Methodology. Hongqi Liu: Methodology. Biyu Hou: Methodology. Xiaozhong Peng: Conceptualization, Methodology. Yang Lu: Conceptualization, Project administration. Guanhua Du: Conceptualization, Project administration, Funding acquisition, Writing - original draft, Writing - review & editing."