Recombinant Zoster Vaccine Is Efficacious and Safe in Frail Individuals.

"data sharing statement anonymized individual participant data and study documents can be requested for further research from www clinicalstudydatarequest com (study id 204878"

"Conflict of Interest Dr Andrew reports grants from the GSK group of companies (GSK) during the study, as well as grants from GSK, the Canadian Frailty Network, the Canadian Institutes of Health Research, the Foundation for Influenza Epidemiology, and grants and personal fees from Sanofi and Pfizer outside the submitted work. Dr Cunningham reports receiving support from GSK to attend conferences, and for a collaborative discovery science project on the vaccine adjuvant used in RZV outside the submitted work. Dr Levin reports grants and fees for Advisory Board from GSK during the study, and is serving as an Advisory Board member for GSK and Merck. Mr Matthews is a freelance consultant for GSK. Dr Schmader reports grants from GSK during the study. Dr McNeil reports grants, personal fees and support for the conduct of clinical trials from GSK and Pfizer, personal fees and support for the conduct of clinical trials from Sanofi Pasteur, as well as personal fees from Merck outside the submitted work. Dr Kim, Mr Dessart, Dr Riley, Dr Schuind and Dr Curran are employees and Dr Oostvogels is a former employee of GSK. Dr Kim, Dr Schuind, Dr Oostvogels and Dr Curran own GSK stock options or (restricted) shares. Dr Oostvogels is employee of CureVac AG and is inventor on a patent owned by GSK and relevant to RZV."

"The authors thank the study participants, investigators, and study teams involved in this trial. We thank Quentin Deraedt, PhD (Modis c/o GSK), for editorial assistance and manuscript coordination. KES was also supported by the National Institute on Aging, Duke Pepper Older Americans Independence Center P30AG028716. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The funding for this study was provided by GlaxoSmithKline Biologicals SA."