Rapid Developability Assessments to Formulate Recombinant Protein Antigens as Stable, Low-Cost, Multi-Dose Vaccine Candidates: Case-Study With Non-Replicating Rotavirus (NRRV) Vaccine Antigens.

Authors:
Sawant N; Kaur K; Holland DA; Hickey JM; Agarwal S and 12 more

Journal:
J Pharm Sci

Publication Year: 2020

DOI:
10.1016/j.xphs.2020.11.039

PMCID:
PMC7884052

PMID:
33285182

Journal Information

Full Title: J Pharm Sci

Abbreviation: J Pharm Sci

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Pharmacology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"The authors would like to thank Bill & Melinda Gates Foundation for providing the financial support for this work (Investment ID OPP1154682). This study was also supported in part by the Koch Institute Support (core) grant P30-CA14051 from the National Cancer Institute. We thank Laura Crowell from the Love lab for comments on the manuscript. The authors wish to acknowledge Drs. Stan Cryz and Bob Sitrin at PATH for providing E. coli cell paste of the NRRV antigens, antibody reagents, ELISA protocols for the competitive ELISA assays, and for helpful and informative discussions."

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Last Updated: Aug 05, 2025