SNPs associated with colorectal cancer at 15q13.3 affect risk enhancers that modulate GREM1 gene expression.

"data availability statement data that support the findings of this study are available in the gene expression omnibus reference number gse77737 (cohen et al 2017 ) and from the encode project ( https://www encodeproject org/ ; davis et al 2018 ; the encode project consortium 2012 ) reference numbers encsr000enm and encsr000emi accessed using the ucsc genome browser. data availability statement data that support the findings of this study are available in the gene expression omnibus reference number gse77737"

"CONFLICT OF INTERESTS The authors declare that there are no conflict of interests."

"This work was supported by NIH/NCI grants CA143237 (GC) and CA204279 (GC). The Genotype‐Tissue Expression (GTEx) Project was supported by the Common Fund of the Office of the Director of the National Institutes of Health, and by NCI, NHGRI, NHLBI, NIDA, NIMH, and NINDS. The data used for the analyses described in this manuscript was obtained from: the GTEx Portal on 07/18/2019. The NHGRI‐EBI GWAS Catalog is funded by NHGRI Grant Number 2U41HG007823, and delivered by collaboration between the NHGRI, EMBL‐EBI, and NCBI. GWAS Catalog data was accessed for this manuscript on 08/09/2020. This study was approved by the Institutional Review Boards of the University of Southern California and the University of Virginia."