TAOK1 is associated with neurodevelopmental disorder and essential for neuronal maturation and cortical development.

"data availability statement all data are available upon request. accession number used for cloning the human taok1: nm_020791"

"CONFLICT OF INTERESTS Mari Rossi is employed by and receives a salary from Ambry Genetics, one of whose commercially available tests is exome sequencing. Amanda Noyes, Katherine G. Langley, Alice Brooks, Jennifer Humberson, Maria J. Guillen Sacoto, Jane Juusola, Kristin G. Monaghan, and Sumit Punj are employees of GeneDx, Inc."

"The authors would like to thank the participating families. We thank all clinicians involved for referring individuals with ID for diagnostic exome sequencing and Dr. Simon McGowan for bioinformatics analysis. This study was supported by the Netherlands Organization for Health Research and Development (ZonMw grant 91718310 to T. K.) and by the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre Programme (AOMW). Additionally, this project has received funding from the European Union's Horizon 2020 RESEArch and INNOVATION PROGRAm under grant agreement No. 779257 (Solve‐RD)."