Multiple cell types contribute to the atherosclerotic lesion fibrous cap by PDGFRβ and bioenergetic mechanisms.

"Competing Interest Statement:: AF declares one competing interest with Amgen Inc. All other authors declare no competing interests."

"Authors acknowledge R. Tripathi for her help isolating and maintaining the lineage-tagged murine SMC line. W. Britt Evans for help in image preprocessing for the automated counting pipeline. R. Adams and R. Klein (MPI) for providing the PdgfrbFL/FL mouse and R. Adams for providing the Cdh5-CreERT2 mouse (MPI). E Pinteaux (University of Manchester) for generating and sharing the Il1r1FL/FL mouse and S. Francis (University of Sheffield) for her advice on the in vivo murine endothelial cell experiments. Myh11-CreERT2 mice are available from Jackson (#019079). V. Newman Albert for aid using Adobe Illustrator. Parts of this work were performed with the assistance of University of Virginia Core Facilities, including the Flow Cytometry Facility, Advanced Microscopy Facility, Genome Technology and Analysis Core, and Bioinformatics Core. This work was supported by NIH R01 grants HL132904, HL136314 and HL141425, as well as a Leducq Fondation Transatlantic Network Grant to GKO. AACN was supported by the Basic and Translational Cardiovascular Training Grant 5 T32 HL 007284-41. VS was supported by the Basic and Translational Cardiovascular Training Grant 5 T32 HL007284-43. RAB was supported by NIH Fellowship F30 HL 136188-04 and the Basic and Translational Cardiovascular Training Grant 5 T32 HL 007284-40. MSR was supported by a Small Research and Travel Grant, Ingrassia Family Echols Scholars Research Grant, and Harrison Undergraduate Research Award."