Development and Relevance of Hypercapnia in COPD.

"Conflicts of Interest Prof. Turner reports nonfinancial support from ResMed, during the conduct of the study, grants from NIHR, grants, personal fees, and nonfinancial support from AstraZeneca, grants and nonfinancial support from Chiesi, grants from Health Foundation, grants from Alpha 1 Foundation, grants from ATS Foundation, and personal fees and nonfinancial support from Boehringer Ingelheim, outside the submitted work. Dr. Mukherjee reports personal fees and nonfinancial support from Pfizer, personal fees from Boehringer Ingelheim, and personal fees from ResMed, outside the submitted work. Prof. Stockley has nor commercial activity or current or past grants that pertain to the current submission but is a member of the COLD scientific committee and contributes annually to the update of the strategy document although does not participate in discussions about publications on which he is an author. Otherwise, the authors declare that there are no conflicts of interest regarding the publication of this article."

"The authors would like to thank members of the Respiratory Physiology Department at Heartlands Hospital who aided sleep study conduct and reporting, and with whom informative discussions about the implications of results occurred. CD was funded during the study by Heartlands Hospital, equipment for sleep studies was provided by ResMed, and funding for review of AATD patients in the PAST was provided by Grifols biotherapeutics. Conflicts of Interest: Prof. Turner reports nonfinancial support from ResMed, during the conduct of the study, grants from NIHR, grants, personal fees, and nonfinancial support from AstraZeneca, grants and nonfinancial support from Chiesi, grants from Health Foundation, grants from Alpha 1 Foundation, grants from ATS Foundation, and personal fees and nonfinancial support from Boehringer Ingelheim, outside the submitted work. Dr. Mukherjee reports personal fees and nonfinancial support from Pfizer, personal fees from Boehringer Ingelheim, and personal fees from ResMed, outside the submitted work. Prof. Stockley has nor commercial activity or current or past grants that pertain to the current submission but is a member of the COLD scientific committee and contributes annually to the update of the strategy document although does not participate in discussions about publications on which he is an author. Otherwise, the authors declare that there are no conflicts of interest regarding the publication of this article."