Discordance Between Patient-Reported Outcomes and Physician-Rated Motor Symptom Severity in Early-to-Middle-Stage Spinocerebellar Ataxia Type 3.

"Declarations Ethics ApprovalThe local medical ethics committee (CMO region Arnhem-Nijmegen) approved the study and written informed consent was obtained from all participants. DisclosuresRoderick Maas and Dennis Schutter report no disclosures. Bart van de Warrenburg receives research support from ZonMw, Hersenstichting, Gossweiler Foundation, Radboud University Medical Center, and uniQure, receives royalties from BSL, Springer Nature, and has served on a scientific advisory board of uniQure. Disclosures Roderick Maas and Dennis Schutter report no disclosures. Bart van de Warrenburg receives research support from ZonMw, Hersenstichting, Gossweiler Foundation, Radboud University Medical Center, and uniQure, receives royalties from BSL, Springer Nature, and has served on a scientific advisory board of uniQure."

"Funding This work is supported by a grant from the Hersenstichting and Brugling fund."