C. elegans detects toxicity of traumatic brain injury generated tau.

"Declaration of Competing Interest Nothing to report."

"This work was supported by Fondazione Regionale per la Ricerca Biomedica (Care4NeuroRare CP_20/2018) to LD; the 10.13039/100000957Alzheimer's Association (AARG-17-532633 to ERZ and RC, AARG-17-505136 to LF); 10.13039/501100002426Fondazione Telethon (Telethon Career Award TCP15011) to LF. LC is the recipient of the 10.13039/100006312BrightFocus award (A2019296F) and the Fondo di Beneficenza - Gruppo Intesa Sanpaolo. C. elegans and OP50 E. coli were provided by the GCG, which is funded by NIH Office Research Infrastructure Programs (P40 OD010440). RB809 strain was provided by the C. elegans Gene Knockout Project at the Oklahoma Medical Research Foundation, which was part of the International C. elegans Gene Knockout Consortium. The authors would like to thank Prof David K Menon for numerous useful discussions. Conceptualization; E.R.Z., R.C., and L.D; Data curation and Formal analysis: E.R.Z., R.C., and L.D; Funding acquisition; E.R.Z., R.C., L.C., L.F. and L.D; Investigation and Methodology: M.M.B., G.V., M.R., L.C., I.B., E.R., C.N., L.COLO., L.R., and E.M.; Project administratio: E.R.Z., R.C., and L.D; Resources: E.R.Z., R.C., L.D., L.C., L.F.; Supervision: E.R.Z., R.C., and L.D; Writing - original draft; E.R.Z., R.C., and L.D; Writing - review & editing: E.R.Z., R.C., and L.D."