SMAD6 transduces endothelial cell flow responses required for blood vessel homeostasis.

"data availability the rna-seq data that support the findings of this study are available in the gene expression omnibus (geo) under the accession number gse147036. data availability the rna-seq data that support the findings of this study are available in the gene expression omnibus (geo) under the accession number gse147036"

"Declarations Conflict of interestThe authors declare no competing interests. Conflict of interest The authors declare no competing interests."

"Funding NIH R01 HL43174, HL116719, HL117256, R35 HL139950 (VLB); NIH-NCI (T32 CA009156), AHA Postdoctoral Fellowship (19POST34380916) (DLR); Integrated Vascular Biology TG (T32HL069768-17), AHA Predoctoral Fellowship (PRE34380887) (DBB); NIH Postbaccalaureate Research Education Program (PREP) (R25GM089569) (SX)."