There is Only One Valid Definition of Clearance: Critical Examination of Clearance Concepts Reveals the Potential for Errors in Clinical Drug Dosing Decisions.
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Full Title: AAPS J
Abbreviation: AAPS J
Country: Unknown
Publisher: Unknown
Language: N/A
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"Declarations Competing InterestsThe authors declare no competing interests. Competing Interests The authors declare no competing interests."
"This work was supported in part by a Mary Anne Koda-Kimble Seed Award for Innovation, UCSF. L.Z.B. is a member of the UCSF Liver Center supported by NIH Grant P30 DK026743. J.K.S. was supported in part by an American Foundation for Pharmaceutical Education Pre-Doctoral Fellowship, NIGMS Grant R25 GM56847, and a Louis Zeh Fellowship. The authors thank Benet lab member Alan Wolfe for suggestions of how to address clearance and mean residence time in the well-stirred model as presented in Supplementary material."
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Last Updated: Aug 05, 2025