Systems Modeling to Quantify Safety Risks in Early Drug Development: Using Bifurcation Analysis and Agent-Based Modeling as Examples.

Authors:
Pin C; Collins T; Gibbs M; Kimko H.

Journal:
AAPS J

Publication Year: 2021

DOI:
10.1208/s12248-021-00580-2

PMCID:
PMC8137611

PMID:
34018069

Journal Information

Full Title: AAPS J

Abbreviation: AAPS J

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Drug Therapy

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Evidence found in paper:

"Declarations Conflict of InterestCP, TC, MG, and HK are employees and shareholders of AstraZeneca Plc. Conflict of Interest CP, TC, MG, and HK are employees and shareholders of AstraZeneca Plc."

Evidence found in paper:

"Funding This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 116030. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation program and EFPIA."

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Last Updated: Aug 05, 2025