Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study.

"Declarations Ethics approval and consent to participateThe protocol of the present study was approved by the Ethics Committee of the Institute of Biomedicine, Anhui Medical University, Hefei, China. All participants signed an approved written consent form. Competing interestsDr. Xiping Xu reports grants from the National Key Research and Development Program [2016YFE0205400, 2018ZX09739010, 2018ZX09301034003), the Science and Technology Planning Project of Guangzhou, China (201707020010), the Science, Technology and Innovation Committee of Shenzhen [GJHS20170314114526143, JSGG20180703155802047), and the Economic, Trade and Information Commission of Shenzhen Municipality [20170505161556110, 20170505160926390]. Dr. Xiao Huang reports grants from the National Natural Science Foundation of China [81960074, 81500233], the Jiangxi Outstanding Person Foundation [20192BCBL23024], and Major projects of the Science and Technology Department, Jiangxi [20171BAB205008]. Dr. Ping Li reports grants from the National Natural Science Foundation of China [81560079, 81860058], Major Projects of the Science and Technology Department, Jiangxi, [20152ACB20022, 20202ACBL206004], Funding Scheme for Academic and Technical Leaders of Major Disciplines, Jiangxi [20172BCB22027], and Special Funds for Guiding Local Scientific and Technological Development by the Central Government of China (S2019CXSFG0016). No other disclosures were reported. The authors declare that they have no competing interests. Competing interests Dr. Xiping Xu reports grants from the National Key Research and Development Program [2016YFE0205400, 2018ZX09739010, 2018ZX09301034003), the Science and Technology Planning Project of Guangzhou, China (201707020010), the Science, Technology and Innovation Committee of Shenzhen [GJHS20170314114526143, JSGG20180703155802047), and the Economic, Trade and Information Commission of Shenzhen Municipality [20170505161556110, 20170505160926390]. Dr. Xiao Huang reports grants from the National Natural Science Foundation of China [81960074, 81500233], the Jiangxi Outstanding Person Foundation [20192BCBL23024], and Major projects of the Science and Technology Department, Jiangxi [20171BAB205008]. Dr. Ping Li reports grants from the National Natural Science Foundation of China [81560079, 81860058], Major Projects of the Science and Technology Department, Jiangxi, [20152ACB20022, 20202ACBL206004], Funding Scheme for Academic and Technical Leaders of Major Disciplines, Jiangxi [20172BCB22027], and Special Funds for Guiding Local Scientific and Technological Development by the Central Government of China (S2019CXSFG0016). No other disclosures were reported. The authors declare that they have no competing interests."

"Funding The study was supported by funding from the following: the National Key Research and Development Program [2016YFE0205400, 2018ZX09739010, 2018ZX09301034003], the Science and Technology Planning Project of Guangzhou, China [201707020010]; the Science, Technology and Innovation Committee of Shenzhen [GJHS20170314114526143, JSGG20180703155802047]; the Economic, Trade and Information Commission of Shenzhen Municipality [20170505161556110, 20170505160926390]; the National Natural Science Foundation of China [81960074, 81860058, 81500233, 81560079]; the Jiangxi Outstanding Person Foundation [20192BCBL23024], the Major Projects of the Science and Technology Department, Jiangxi [20171BAB205008, 20152ACB20022, 20202ACBL206004], the Funding Scheme for Academic and Technical Leaders of Major Disciplines, Jiangxi [20172BCB22027], and Special Funds for Guiding Local Scientific and Technological Development by the Central Government of China (S2019CXSFG0016)."

"Trial registration ChiCTR1800017274."