Local excision and treatment of early node-negative anal squamous cell carcinomas in a highly HIV prevalent population.

"Declarations Conflict of interestThe authors do not have any conflicts of interest to declare. Ethical approvalThe authors confirm that the study has been approved by the London-Westminster Research and Ethics Committee and certify that the study was performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards. Consent to participateStudy participants were consented to take part in the study if they were still undergoing treatment at our clinical centre. Retrospective historical patients within the 20-year cohort who could not be reasonably contacted were not consented to take part, however, permission for this study design was sought and granted from the Research and Ethics Committee prior to commencement of the study. Consent for publicationAll named authors have contributed to this research and give their consent for publication. Conflict of interest The authors do not have any conflicts of interest to declare."

"Funding This work represents independent research supported by the National Institute for Health Research (NIHR) Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and the Institute of Cancer Research, London. The views expressed are those of the authors and not necessarily those of the NIHR or the Department of Health and Social Care."