Physical activity and the risk of SARS-CoV-2 infection, severe COVID-19 illness and COVID-19 related mortality in South Korea: a nationwide cohort study.

"we generated the eight cohorts for robustness and generalisation of our results ( online supplemental table s1 and figure 1 ): (1) cohort a was the main study that consisted of participants who received general health examination between 2018 and 2019 ( online supplemental figures s1 and s2 ; n=76 395); (2) propensity score matched cohort a was performed by matching two groups (insufficient aerobic and muscle strengthening vs aerobic and muscle strengthening; n=5298); (3) cohort b consisted of only covid-19 confirmed patients in cohort a (n=1293); (4) cohort c was conducted differential conditions of 'exposure' using the met score ( online supplemental figures s3 and s4 ; n)=76 395); (5) propensity score matched cohort c was performed by matching two groups (insufficient physical activity group (0-500 met min/week) vs sufficient physical activity group (more than 500 met min/week); n=59 986); (6) cohort d consisted of participants who received general health examination between 2015 and 2019 ( online supplemental figures s5 and s6 ; n=118 768); (7) propensity score matched cohort d was performed by matching two groups (insufficient physical activity group (0-500 met min/week) vs sufficient physical activity group (more than 500 met min/week); n=23 860); and (8) cohort e consisted of only covid-19 confirmed patients in cohort c (n=3882) 10 1136/bjsports-2021-104203 supp10 supplementary data 10 1136/bjsports-2021-104203 supp1 supplementary data 10 1136/bjsports-2021-104203 supp2 supplementary data 10 1136/bjsports-2021-104203 supp3 supplementary data 10 1136/bjsports-2021-104203 supp4 supplementary data 10 1136/bjsports-2021-104203 supp5 supplementary data 10 1136/bjsports-2021-104203 supp6 supplementary data figure 1 participant profile in all cohort.; a two-sided p value of less than 0 05 was considered statistically significant 10 1136/bjsports-2021-104203 supp7 supplementary data 10 1136/bjsports-2021-104203 supp8 supplementary data 10 1136/bjsports-2021-104203 supp9 supplementary data no patients were directly involved in designing the research question or in conducting the research."

"Competing interests: None declared."

"Funding: This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (NRF2019R1G1A109977913)."