Temporal Expression Pattern of Hemoxygenase-1 Expression and Its Association with Vasospasm and Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage.

"Conflict of interest The authors declare that they have no conflict of interest."

"Source of Support Open Access funding enabled and organized by Projekt DEAL. German Research Foundation Grant to NS: SCHA 1838/4–1. Funded by the Berta-Ottenstein-Programme for Advanced Clinician Scientists, Faculty of Medicine, University of Freiburg (NS)."

"A total of 66 patients with spontaneous SAH (19 men, 47 women, aged 58.03 ± 13.22 years, range 27–88 years, Table ) admitted to either the intensive care units (ICUs) of the Department of Neurology and Neuroscience or the Department of Neurosurgery at the University of Freiburg (Germany) Medical Center between 2017 and 2020 were included in this study. The study protocol was approved by the Institutional Ethics Review Board of the University of Freiburg (Protocol no. 293/15). Informed consent from the patient, legal guardian, or by proxy was provided. The trial was registered with the German Clinical Trials Register (Trial-ID DRKS00008981; Universal Trial Number U1111-1172-6077)."