Testing and correcting for weak and pleiotropic instruments in two-sample multivariable Mendelian randomization.

Authors:
Sanderson E; Spiller W; Bowden J.

Journal:
Stat Med

Publication Year: 2021

DOI:
10.1002/sim.9133

PMCID:
PMC9479726

PMID:
34338327

View on PubMed View on PMC View Publisher
Journal Information

Full Title: Stat Med

Abbreviation: Stat Med

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Statistics as Topic

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

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Core Indicators
Evidence found in paper:

"data availability statement details and data for the data used in this article are available at https://github com/wspiller/mrchallenge2019."

Evidence found in paper:

"the mvmr package is available to download at https://github com/wspiller/mvmr/.; the code used to conduct the simulations and applied analysis is available at https://github com/eleanorsanderson/mvmrweakinstruments.; the mvmr package is available at https://github com/wspiller/mvmr/.; data availability statement details and data for the data used in this article are available at https://github com/wspiller/mrchallenge2019."

COI Disclosure
Evidence found in paper:

"Funding information Medical Research Council, MC_UU_00011/1; MC_UU_00011/2; Wellcome Trust, 108902/B/15/Z"

Protocol Registration
Open Access
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Replication
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Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025