Percutaneous cryoneurolysis of the lateral femoral cutaneous nerve for analgesia following skin grafting: a randomized, controlled pilot study.

"Competing interests: Drs. Finneran, Swisher, and Ilfeld: The University of California has received funding and product for other research projects from cryoneurolysis manufacturer Epimed (Farmers Branch, TX); infusion pump manufacturer InfuTronix (Natick, MA); and a manufacturer of a peripheral nerve stimulation device, SPR Therapeutics (Cleveland, OH). Drs. Godat, Higginson, and Lee; and Mr. Schaar: no additional conflicts."

"Funding: Epimed International (Farmers Branch, TX) provided the cryoneurolysis devices used for this pilot study."

"The protocol was approved by the UC San Diego Institutional Review Board (number 180863, San Diego, California) and prospectively registered at clinicaltrials.gov (NCT03578237; Brian M. Ilfeld, MD, MS; 25 June 2018). Enrollment was offered to adult burn patients undergoing STSG with a planned LFCN block. Exclusion criteria included daily opioid use for a duration of at least 4 weeks, morbid obesity, incarceration, pregnancy, and medical contraindications to cryoneurolysis. "